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Functional transplantable B-cells generated from mice

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Stem cells generated from mice have shown to be functional when transplanted, leading to the possibility of future therapies… Functional B1-cells that have been derived from mouse embryonic stem cells have been found to be capable of long-term engraftment as they secrete natural antibodies after transplantation. Scientists were interested in B1-cells generated from pluripotent stem cells because they could be tested as a therapeutic for a broad range of immunological disorders. “It is still challenging to produce transplantable immune cells from mouse embryonic stem cells, so obtaining transplantable functional B1-cells from mouse embryonic stem cells is a significant advance in the field,” said senior study author Dr Momoko Yoshimoto of the Center for Stem Cell & Regenerative Medicine at the McGovern Medical School at UTHealth in Houston. “The take-home message is that a portion of immune cells may be replaced by cell therapies utilising pluripotent stem ce...

New, unproven stem cell treatment danger

Consumer Reports Thursday, February 07, 2019 05:57AM The Food and Drug Administration issued a warning after a dozen people were hospitalized with bacterial infections following unapproved stem cell treatments. Consumer Reports has important safety tips to help keep you and your family safe. Health officials say the patients in Arizona, Florida and Texas suffered from bacterial infections after getting unapproved stem cell shots contaminated with E. coli and other bacteria. The FDA says it is "focusing more resources on enforcement when we see companies skirt safety measures and put patients at risk." No doubt a reference to the booming network of private clinics that are promoting and administering stem cell therapies for unapproved and unproven uses like treating COPD or diabetes. In fact, stem cell treatments are only widely accepted to treat blood disorders like leukemia and some forms of anemia and in some cases to help burn victims. ...